Anti-notch3 agonist antibodies and their use in the treatment of notch3-related diseases
US8187839B2 · kind B2 · utility
3Cited by
11References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 23, 2011 |
| Grant date | May 29, 2012 |
| Priority date | — |
| Expiry date | Feb 23, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.