Patent · US Active

Gyrase inhibitors and uses thereof

US8188095B2 · kind B2 · utility

11Cited by

12References

6Claims

0Family size

Assignee

Vertex Pharmaceuticals Incorporated · US

Inventors

Paul S. Charifson · Framingham, US
David Deininger · New Brunswick, US
Anne-Laure Grillot · Cambridge, US
Yusheng Liao · Lexington, US
Steven Ronkin · Watertown, US
Dean Stamos · Carlsbad, US
Emanuele Perola · Cambridge, US
Tiansheng Wang · Concord, US
Arnaud Le Tiran · Chatou, FR
Joseph Drumm · Westborough, US

Key dates

Filing date	Oct 7, 2008
Grant date	May 29, 2012
Priority date	—
Expiry date	Jul 29, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to compounds which inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.