Patent · US Active

Gyrase inhibitors and uses thereof

US8193352B2 · kind B2 · utility

11Cited by

5References

18Claims

0Family size

Assignee

Vertex Pharmaceuticals Incorporated · US

Inventors

Paul S. Charifson · Framingham, US
David Deininger · New Brunswick, US
Anne-Laure Grillot · Cambridge, US
Yusheng Liao · Lexington, US
Steven Ronkin · Watertown, US
Dean Stamos · Carlsbad, US
Emanuele Perola · Cambridge, US
Tiansheng Wang · Concord, US
Arnaud LeTiran · Lexington, US
Joseph Drumm · Westborough, US

Key dates

Filing date	Sep 2, 2009
Grant date	Jun 5, 2012
Priority date	—
Expiry date	Sep 18, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to compounds that inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.