Quaternary ammonium compounds useful as muscarinic receptor antagonists
US8202891B2 · kind B2 · utility
2Cited by
9References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 23, 2008 |
| Grant date | Jun 19, 2012 |
| Priority date | — |
| Expiry date | Mar 20, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides compounds of the formula:in salt or zwitterionic form or a pharmaceutically acceptable salt thereof, wherein R1-6, a, Z and Q are as defined in the specification. These compounds are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes for preparing such compounds and methods of using such compounds to, for example, treat pulmonary disorders such as chronic obstructive pulmonary disease and asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.