PSM peptides as vaccine targets against methicillin-resistant Staphylococcus

US8211445B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Michael Otto · Lilburn, US
• Rong Wang · Mianyang, CN

Key dates

• Filing date: Dec 4, 2009
• Grant date: Jul 3, 2012
• Expiry date: Jan 14, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/31
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This disclosure concerns compositions and methods for the treatment and inhibition of infectious disease, particularly methicillin-resistant Staphylococcus. In certain embodiments, the disclosure concerns immunogenic peptides, for instance PSM peptides, which can be used to induce protective immunity against methicillin-resistant Staphylococcus. Also disclosed are methods of detecting methicillin-resistant staphylococcus in a sample, and methods of diagnosing methicillin-resistant staphylococcus in a subject.