Methods of treating inflammatory disease using a soluble IL-20 receptor
US8217008B2 · kind B2 · utility
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23References
15Claims
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Key dates
| Filing date | Oct 7, 2010 |
| Grant date | Jul 10, 2012 |
| Priority date | — |
| Expiry date | Oct 7, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A soluble receptor to IL-20 having two polypeptide subunits, IL-20RA (formerly called ZcytoR7) and IL-20RB (formerly called DIRS1). The two subunits are preferably linked together. In one embodiment one subunit is fused to the constant region of the light chain of an immunoglobulin, and the other subunit is fused to the constant region of the heavy chain of the immunoglobulin. The light chain and the heavy chain are connected via a disulfide bond.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.