Patent · US Active

Method for preparing enantiomerically pure 4-pyrrolidino phenylbenzyl ether derivatives

US8227505B2 · kind B2 · utility

0Cited by

7References

6Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Stefan Hildbrand · Riehen, CH
Bruno Lohri · Kaiseraugst, CH
Wolfgang Wostl · Weil am Rhein, DE

Key dates

Filing date	Jan 26, 2009
Grant date	Jul 24, 2012
Priority date	—
Expiry date	Feb 2, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/07
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a method for preparing enantiomerically pure 4-pyrrolidinophenylbenzyl ether derivatives of formula I:wherein R1, R21, R22, R23, R24 and n are as defined in the description and claims and to intermediates useful in the method of the invention as well as salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.