Multiple CpG oligodeoxynucleotide and their use to induce an immune response

US8232259B2 · kind B2 · utility

Assignee

• The United States of America as Represented by the Secretary of the Department of Health and Human Services · US

Inventors

• Dennis Klinman · Potomac, US
• Ken Ishii · Columbia, US
• Daniela Verthelyi · Potomac, US

Key dates

• Filing date: Feb 11, 2011
• Grant date: Jul 31, 2012
• Expiry date: Feb 11, 2031

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compositions including multiple oligodeoxynucleotides with a CpG motif are disclosed herein. The compositions can include either D or K type oligodeoxynucleotides. These compositions are of use in inducing an immune response in a large percentage of the individuals in a population.