Patent · US Active

Inhibitors of the interaction between MDM2 and P53

US8232298B2 · kind B2 · utility

1Cited by

3References

17Claims

0Family size

Assignee

Janssen Pharmaceutica NA · BE

Inventors

Jean Fernand Armand Lacrampe · Le Mesnil-Esnard, FR
Christophe Meyer · Oissel, FR
Bruno Schoentjes · Bois-Guillaume, FR
Delphine Yvonne Raymonde Lardeau · Issy-les-Moulineaux, FR
Alain Philippe Poncelet · Bayeux, FR
Luc Van Hijfte · Saint-Étienne-du-Rouvray, FR

Key dates

Filing date	Mar 19, 2007
Grant date	Jul 31, 2012
Priority date	—
Expiry date	Feb 22, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, s, t, R1, R2, A and Z have defined meanings.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.