C(10) ethyl ester and C(10) cyclopropyl ester substituted taxanes
US8242166B2 · kind B2 · utility
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Key dates
| Filing date | Mar 24, 2009 |
| Grant date | Aug 14, 2012 |
| Priority date | — |
| Expiry date | Sep 16, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Taxanes having an ethyl ester or cyclopropyl ester substituent at C(10), a keto substituent at C(9), a hydroxy substituent at C(7), a thienyl substituent at C(3′) and a cyclobutyloxycarbamate or cyclopentyloxycarbamate substituent at C(3′), pharmaceutical compositions comprising such taxanes, methods of treatment and administration, and methods of preparation of medicaments comprising the taxanes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.