Duplex oligonucleotide complexes and methods for gene silencing by RNA interference
US8252755B2 · kind B2 · utility
18Cited by
181References
7Claims
0Family size
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Key dates
| Filing date | Sep 20, 2007 |
| Grant date | Aug 28, 2012 |
| Priority date | — |
| Expiry date | Mar 21, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2330/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are duplex oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene without the aid of a transfection reagent(s). The duplex oligonucleotide complexes of the disclosure include a conjugate moiety that facilitates delivery to a cell, tissue or organism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.