Antibody targeting compounds
US8252902B2 · kind B2 · utility
26Cited by
18References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 22, 2002 |
| Grant date | Aug 28, 2012 |
| Priority date | — |
| Expiry date | Jul 7, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides antibody targeting compounds in which the specificity of the antibody has been reprogrammed by covalently or noncovalently linking a targeting agent to the combining site of an antibody. By this approach, the covalently modified antibody takes on the binding specificity of the targeting agent. The compound may have biological activity provided by the targeting agent or by a separate biological agent. Various uses of the invention compounds are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.