Compositions and methods for modulation of LMNA expression
US8258109B2 · kind B2 · utility
25Cited by
7References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 17, 2006 |
| Grant date | Sep 4, 2012 |
| Priority date | — |
| Expiry date | Nov 23, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/33
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are compounds, compositions and methods for modulating the expression of LMNA in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders. Further provided are methods of identifying cis splicing regulatory elements of a selected mRNA using the disclosed compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.