Systems and methods for baseline correction using non-linear normalization
US8265883B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 23, 2011 |
| Grant date | Sep 11, 2012 |
| Priority date | — |
| Expiry date | Mar 23, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/12746
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Systems and methods are provided for calibrating emission data or other information signals collected during a polymerase chain reaction (PCR), amplification reaction, assay, process, or other reaction. Calibration of multiple detectable materials can be achieved during a single cycle or run, or during a plurality of runs of the reaction. A reading from every well, container, or other support region of a sample support does not have to be taken. Interpolation can be used to determine values for emission data or other information signals that were not taken, or are unknown, using detected emission data, or other detected information signals. By calibrating the detected emission data and the interpolated data, a more accurate reading of emission data or information signal can be obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.