Substituted naphthyridine compounds as inhibitors of Akt activity
US8288407B2 · kind B2 · utility
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2References
4Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 11, 2011 |
| Grant date | Oct 16, 2012 |
| Priority date | — |
| Expiry date | Mar 11, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer. Compounds disclosed herein have the following chemical structure:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.