Patent · US Active

CETP inhibitors derived from benzoxazole arylamides

US8293721B2 · kind B2 · utility

7Cited by

2References

13Claims

0Family size

Assignee

Merck Sharp & Dohme LLC · US

Inventors

Julianne A. Hunt · Scotch Plains, US
Ramzi F. Sweis · Vernon Hills, US
Peter J. Sinclair · Highland Park, US

Key dates

Filing date	Jun 16, 2008
Grant date	Oct 23, 2012
Priority date	—
Expiry date	Nov 14, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D413/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are potent CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In formula I, A-B is an arylamide moiety.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.