Processes and intermediates

US8293929B2 · kind B2 · utility

Assignee

• Vertex Pharmaceuticals Incorporated · US

Inventors

• Gerald J. Tanoury · Marlborough, US
• Minzhang Chen · Acton, US
• Andrew Jones · Lexington, US
• Philip Nyce · Millbury, US
• Martin Trudeau · Shannon, US
• David Joseph Guerin · Natick, US
• John R. Snoonian · Bolton, US

Key dates

• Filing date: Oct 12, 2010
• Grant date: Oct 23, 2012
• Expiry date: Oct 12, 2030

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to processes and compounds useful for producing modified aspartic acid derivatives, such as aspartic acid aldehyde moieties. Aspartic acid derivatives are useful for preparing caspase inhibitors and/or prodrugs thereof.