Pyrazolopyridine, indazole, imidazopyridine, imidazopyrimidine, pyrazolopyrazine and pyrazolopyridine derivatives as stimulators of guanylate cyclase for cardiovascular disorders

US8309551B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Hartmut Schirok · Wuppertal, DE
• Joachim Mittendorf · Wuppertal, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Frank Wunder · Wuppertal, DE
• Friederike Stoll · Mülheim an der Ruhr, DE
• Karl-Heinz Schlemmer · Wuppertal, DE

Key dates

• Filing date: Sep 1, 2007
• Grant date: Nov 13, 2012
• Expiry date: Mar 19, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel azabicyclic compounds, processes for their preparation, their use alone or in combinations for the treatment and/or prevention of diseases, and their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.