Compositions and methods for inducing cell dedifferentiation
US8309555B2 · kind B2 · utility
4Cited by
8References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2009 |
| Grant date | Nov 13, 2012 |
| Priority date | — |
| Expiry date | Dec 9, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides 2,6-disubstituted purine compounds, compositions and methods for dedifferentiating lineage committed mammalian cells into stem cells. The present invention also provides methods of inducing dedifferentiation of lineage committed mammalian cells into stem cells, which can be further differentiated into various lineage committed cells. Methods of identifying additional 2,6-disubstituted purine compounds useful for inducing dedifferentiation of lineage committed cells into stem cells are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.