Patent · US Active

Substituted pyridines as GPBAR1 agonists

US8309734B2 · kind B2 · utility

20Cited by

0References

3Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Caterina Bissantz · Rixheim, FR
Henrietta Dehmlow · Weil am Rhein, DE
Rainer E. Martin · Basel, CH
Ulrike Obst Sander · Sursee, CH
Hans Richter · Weil am Rhein, DE
Christoph Ullmer · Fischingen, DE

Key dates

Filing date	Oct 19, 2009
Grant date	Nov 13, 2012
Priority date	—
Expiry date	Oct 19, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to novel phenyl amide or pyridyl amide derivatives of the formulawherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.