Compounds and methods for improving cellular uptake of oligomeric compounds
US8318496B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Oct 6, 2008 |
| Grant date | Nov 27, 2012 |
| Priority date | — |
| Expiry date | Nov 15, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides method of optimizing the efficacy and potency of antisense drugs. In certain embodiments, the invention provides assays useful for determining favorable oligonucleotide characteristics and excipeints for improved cellular uptake.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.