Bioactive FUS1 peptides and nanoparticle-polypeptide complexes
US8338366B2 · kind B2 · utility
7Cited by
17References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 14, 2006 |
| Grant date | Dec 25, 2012 |
| Priority date | — |
| Expiry date | Oct 17, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4703
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nanoparticle-polypeptide complex comprising a bioactive polypeptide in association with a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the protein. The polypeptide can be a protein or a peptide. In some embodiments, the amino acid sequence of the protein or peptide is derived from the amino acid sequence of a tumor suppressor gene product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.