Inventor · Houston, TX, US

Jack A. Roth

40Patents
11h-index
39Co-inventors
75Inventor score

Filing activity: Dec 30, 1985 → Oct 12, 2017

Most-cited inventions

PatentTitleAreaCited byStatus
US6069134A Methods and compositions comprising DNA damaging agents and p53 Chemistry; Metallurgy 88 Expired
US5747469A Methods and compositions comprising DNA damaging agents and p53 Chemistry; Metallurgy 60 Expired
US6143290A Tumor regression by adenovirus expression of wild-type p53 Chemistry; Metallurgy 53 Expired
US6410010B1 Recombinant P53 adenovirus compositions Chemistry; Metallurgy 34 Expired
US6110744A Diminishing viral gene expression by promoter replacement Chemistry; Metallurgy 27 Expired
US6511847B1 Recombinant p53 adenovirus methods and compositions Chemistry; Metallurgy 20 Expired
US5958892A 2-methoxyestradiol-induced apoptosis in cancer cells Human Necessities 18 Expired
US6482803B1 Modification of mutated P53 gene in tumors by retroviral delivery of ribozyme A Chemistry; Metallurgy 18 Expired
US6017524A Inhibiting the growth p53 deficient tumor cells by administering the p53 gene Human Necessities 17 Expired
US6627189B1 Inhibition of cellular proliferation using ras antisense molecules Human Necessities 16 Expired
US6410029B1 2-methoxyestradiol-induced apoptosis in cancer cells Human Necessities 12 Expired
US7109179B2 Methods and compositions comprising DNA damaging agents and p53 Chemistry; Metallurgy 11 Expired
US6797702B1 Methods and compositions comprising DNA damaging agents and P53 Chemistry; Metallurgy 10 Expired
US5637456A Rapid test for determining the amount of functionally inactive gene in a gene therapy vector preparation Chemistry; Metallurgy 10 Expired
US7252989B1 Adenovirus supervector system Chemistry; Metallurgy 8 Expired
US6630344B1 Diminishing viral gene expression by promoter replacement Chemistry; Metallurgy 8 Expired
US8338366B2 Bioactive FUS1 peptides and nanoparticle-polypeptide complexes Chemistry; Metallurgy 7 Active
US6133416A Inhibition of cell growth by an anti-proliferative factor Chemistry; Metallurgy 6 Expired
US6251871A P16 expression constructs and their application in cancer therapy Chemistry; Metallurgy 6 Expired
US6998117B1 Cancer treatment with retroviral vectors comprising wild-type p53 Human Necessities 6 Expired
US7163925B1 p16 expression constructs and their application in cancer therapy Chemistry; Metallurgy 5 Expired
US6436700B1 Anti-sense p21 k-ras Human Necessities 5 Expired
US6805858B1 Methods for the administration of adenovirus p53 Chemistry; Metallurgy 4 Expired
US6740320B1 Recombinant P53 adenovirus methods and compositions Chemistry; Metallurgy 4 Expired
US4704064A Paper roll elevator lift Emerging Cross-Sectional Technologies 3 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.