Substituted pyrido(3,2-D) pyrimidines and pharmaceutical compositions for treating viral infections
US8338435B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 20, 2007 |
| Grant date | Dec 25, 2012 |
| Priority date | — |
| Expiry date | Mar 25, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides di-, tri- and tetra-substituted pyrido(3,2-d)pyrimidine derivatives with specific substituting patterns, their pharmaceutically acceptable salts, N-oxides, solvates, pro-drugs and enantiomers, possessing unexpectedly desirable pharmaceutical properties, in particular being highly active antiviral agents. The invention also provides use of such derivatives in the treatment of viral infections and pathologic conditions associated therewith, including hepatitis C.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.