4-dimethylaminobutyric acid derivatives
US8344027B2 · kind B2 · utility
1Cited by
2References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 2009 |
| Grant date | Jan 1, 2013 |
| Priority date | — |
| Expiry date | Oct 29, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel 4-dimethylaminobutyric acid derivatives of the formulawherein A1, A2, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments in methods for the treatment of diseases modulated by CPT2 inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.