Inhibitors of phosphatidylinositol 3-kinase

US8344153B2 · kind B2 · utility

Assignee

• Vertex Pharmaceuticals Incorporated · US

Inventors

• Kevin Michael Cottrell · Cambridge, US
• Alex Aronov · Newton, US
• Robert J. Davies · Arlington, US
• Jon Come · Cambridge, US
• David Messersmith · Somerville, US
• Jinwang Xu · Framingham, US
• Upul K. Bandarage · Lexington, US
• Jingrong Cao · Newton, US

Key dates

• Filing date: Jun 9, 2010
• Grant date: Jan 1, 2013
• Expiry date: Jul 6, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.