Patent · US Active

Spiro-imidazolone derivatives as glucagon receptor antagonists

US8361959B2 · kind B2 · utility

2Cited by

0References

18Claims

0Family size

Assignee

Merck Sharp & Dohme LLC · US

Inventors

Andrew Stamford · Madison, US
Michael Miller · Scotch Plains, US
Duane DeMong · Somerville, US
William J. Greenlee · Teaneck, US
Joseph A. Kozlowski · Princeton, US
Brian J. Lavey · New Providence, US
Michael K. C. Wong · New Brunswick, US
Wensheng Yu · Edison, US
Xing Dai · Cranford, US
De-Yi Yang · Morristown, US
Guowei Zhou · Somerville, US

Key dates

Filing date	Sep 30, 2009
Grant date	Jan 29, 2013
Priority date	—
Expiry date	Dec 11, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds of the general formula: (I) wherein ring A, ring B, R1, R3, Z, L1, and L2 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and to methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.