Patent · US Active

Primary amine diazeniumdiolate heterocyclic derivatives

US8361994B2 · kind B2 · utility

1Cited by

14References

32Claims

0Family size

Assignee

Merck Sharp & Dohme LLC · US

Inventors

Amjad Ali · Freehold, US
Michael Man-Chu Lo · Rahway, US
Zhiqiang Guo · San Diego, US
Brent Whitehead · Piscataway, US
Timothy J. Henderson · Natick, US
Lin Yan · East Brunswick Township, US
Shrenik K. Shah · Metuchen, US

Key dates

Filing date	Mar 5, 2012
Grant date	Jan 29, 2013
Priority date	—
Expiry date	Mar 5, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A compound having the structureuseful for treating hypertension, Pulmonary Arterial Hypertension (PAH), congestive heart failure, conditions resulting from excessive water retention, cardiovascular disease, diabetes, oxidative stress, endothelial dysfunction, cirrhosis, pre-eclampsia, osteoporosis or nephropathy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.