Patent · US Active

Azetidines as MEK inhibitors for the treatment of proliferative diseases

US8362002B2 · kind B2 · utility

7Cited by
6References
63Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 15, 2011
Grant dateJan 29, 2013
Priority date
Expiry dateMar 15, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.