Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

US8362253B2 · kind B2 · utility

Assignee

• Vertex Pharmaceuticals Incorporated · US

Inventors

• John DeMattei · San Diego, US
• Yushi Feng · Zionsville, US
• Cristian Harrison · Beverly, US
• Adam Looker · Newton, US
• Praveen Mudunuri · Waltham, US
• Stefanie Roeper · Medford, US
• Yuegang Zhang · Wayland, US

Key dates

• Filing date: Mar 6, 2012
• Grant date: Jan 29, 2013
• Expiry date: Mar 6, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D215/233
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide are described herein, including crystalline forms thereof.