Patent · US Active

Bicyclo-substituted pyrazolon azo derivatives, preparation process and pharmaceutical use thereof

US8367710B2 · kind B2 · utility

2Cited by
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25Claims
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Key dates

Filing dateJan 4, 2009
Grant dateFeb 5, 2013
Priority date
Expiry dateJun 11, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The bicyclo-substituted pyrazolon-azo derivatives of formula (I) or pharmaceutical acceptable salts, hydrates or solvates thereof, methods for their preparation, pharmaceutical compositions containing the same and their use as a therapeutic agent, especially as thrombopoietin (TPO) mimetics and their use as agonists of thrombopoietin receptor are disclosed. The definition of substituents in formula (I) are the same as defined in the description.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.