Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA
US8372816B2 · kind B2 · utility
7Cited by
1References
57Claims
0Family size
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Inventor
Key dates
| Filing date | Apr 5, 2010 |
| Grant date | Feb 12, 2013 |
| Priority date | — |
| Expiry date | Apr 5, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to compounds, compositions, and methods useful for reducing KRAS target RNA and protein levels via use of Dicer substrate siRNA (DsiRNA) agents possessing asymmetric end structures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.