Patent · US Active

Pyrimidyl cyclopentanes as AKT protein kinase inhibitors

US8377937B2 · kind B2 · utility

12Cited by
25References
37Claims
0Family size

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Key dates

Filing dateJul 3, 2008
Grant dateFeb 19, 2013
Priority date
Expiry dateFeb 15, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.