Patent · US Active

Preparation of protected alpha-keto beta-amino esters and amides

US8378124B2 · kind B2 · utility

1Cited by

3References

7Claims

0Family size

Assignee

Vertex Pharmaceuticals Incorporated · US

Inventors

William A. Nugent · Wilmington, US
Adam Looker · Newton, US
Raymond E. Forslund · Natick, US
Theodore A. Martinot · Brookline, US
Cristian Harrison · Beverly, US
Shereen Ibrahim · Cambridge, US

Key dates

Filing date	Dec 30, 2010
Grant date	Feb 19, 2013
Priority date	—
Expiry date	Dec 30, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides β-sulfonamide α-keto esters and amides in which the α-keto is protected as a 1,3-dithiolane derivative. Also provided are methods for preparing such esters and amides and for incorporating them into peptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.