Aegyptin and uses thereof

US8383589B2 · kind B2 · utility

Assignees

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US
• The Regents of the University of California · US

Inventors

• Eric Calvo · Bethesda, US
• Osvaldo Marinotti · Aliso Viejo, US
• Jose M. C. Ribeiro · Rockville, US
• Ivo M. Francischetti · Washington, US

Key dates

• Filing date: Jul 7, 2008
• Grant date: Feb 26, 2013
• Expiry date: Aug 21, 2029

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed.