Patent · US Active

Aminobenzoquinazolinone M1 receptor positive allosteric modulators

US8383638B2 · kind B2 · utility

5Cited by
3References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 13, 2010
Grant dateFeb 26, 2013
Priority date
Expiry dateDec 13, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention is directed to aminobenzoquinazolinone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.