Patent · US Active

Fc variants

US8388955B2 · kind B2 · utility

53Cited by

93References

4Claims

0Family size

Assignee

Xencor, Inc. · US

Inventors

Gregory Alan Lazar · Los Angeles, US
Wei Dang · Pasadena, US
John Desjarlais · Pasadena, US
Sher Bahadur Karki · Pasadena, US
Omid Vafa · Monrovia, US
Robert Hayes · Paoli, US
Jost Vielmetter · Altadena, US

Key dates

Filing date	Jun 15, 2007
Grant date	Mar 5, 2013
Priority date	—
Expiry date	Aug 11, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/77
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to Fc variants having increased affinity for FcγRIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.