Isoxazoles / O-pyridines with ethyl and ethenyl linker
US8389550B2 · kind B2 · utility
3Cited by
1References
18Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Feb 17, 2010 |
| Grant date | Mar 5, 2013 |
| Priority date | — |
| Expiry date | Aug 16, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is concerned with novel isoxazole-pyridines of formula Iwherein R1, R2, R3 and L are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of the present invention have affinity and selectivity for GABA A α5 receptor. Further the present invention is concerned with the manufacture of the active compounds of formula I, pharmaceutical compositions containing them and their use as pharmaceutical agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.