Patent · US Active

Pyrrolidine derivatives as NK2 receptor antagonists

US8404679B2 · kind B2 · utility

1Cited by

1References

10Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Caterina Bissantz · Rixheim, FR
Philippe Jablonski · Steinbrunn-le-Haut, FR
Henner Knust · Rheinfelden (Baden), DE
Andreas Koblet · Bottmingen, CH
Anja Limberg · Penzberg, DE
Matthias Nettekoven · Weil am Rhein, DE
Hasane Ratni · Habsheim, FR
Claus Riemer · Glückstadt, DE

Key dates

Filing date	Apr 23, 2012
Grant date	Mar 26, 2013
Priority date	—
Expiry date	Apr 23, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D413/10
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to compounds of formula Iwherein R1, R2, R3, Ar and n are as defined herein and pharmaceutically active salts, racemic mixtures, enantiomers, optical isomers or tautomeric forms thereof. The compounds can be used for the treatment of depression, anxiety or schizophrenia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.