Single chain multivalent binding proteins with effector function

US8409577B2 · kind B2 · utility

Assignee

• EMERGENT PRODUCT DEVELOPMENT SEATTLE, LLC · US

Inventors

• Peter Armstrong Thompson · Bellevue, US
• Jeffrey A. Ledbetter · Shoreline, US
• Martha Hayden-Ledbetter · Shoreline, US
• Laura Sue Grosmaire · Hobart, US
• Robert F. Bader · Los Angeles, US
• William Brady · Edmonds, US

Key dates

• Filing date: Jun 12, 2007
• Grant date: Apr 2, 2013
• Expiry date: Mar 22, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Multivalent binding peptides, including bi-specific binding peptides, having immunoglobulin effector function are provided, along with encoding nucleic acids, vectors and host cells as well as methods for making such peptides and methods for using such peptides to treat or prevent a variety of diseases, disorders or conditions, as well as to ameliorate at least one symptom associated with such a disease, disorder or condition.