Patent · US Active

1′-substituted-carba-nucleoside prodrugs for antiviral treatment

US8415308B2 · kind B2 · utility

92Cited by
6References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 2011
Grant dateApr 9, 2013
Priority date
Expiry dateMay 26, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are prodrugs of pyrrolo[1,2-f][1,2,4]triazin-7-yl nucleoside phosphates wherein the 1′ position of the nucleoside sugar is substituted with CN. The compounds, compositions, and methods provided are useful for the treatment Hepatitis C infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.