Inhibitors of Janus kinases
US8415346B2 · kind B2 · utility
1Cited by
1References
8Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 21, 2009 |
| Grant date | Apr 9, 2013 |
| Priority date | — |
| Expiry date | Jul 21, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2). The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 and TYK2 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.