C-21-keto lupane derivatives preparation and use thereof
US8431556B2 · kind B2 · utility
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21Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 3, 2010 |
| Grant date | Apr 30, 2013 |
| Priority date | — |
| Expiry date | Apr 17, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to 21-keto triterpene compounds of formula (I):wherein R1, X and Y are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infections by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.