Inhibitors of janus kinases
US8431569B2 · kind B2 · utility
1Cited by
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10Claims
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Key dates
| Filing date | Dec 9, 2008 |
| Grant date | Apr 30, 2013 |
| Priority date | — |
| Expiry date | Jun 28, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.