Patent · US Active

Deacetylase inhibitors and uses thereof

US8440716B2 · kind B2 · utility

12Cited by
56References
19Claims
0Family size

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Inventors

Key dates

Filing dateJul 22, 2009
Grant dateMay 14, 2013
Priority date
Expiry dateMar 14, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C251/86
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides novel compounds of formula (I) and pharmaceutical compositions thereof. The inventive compounds are useful as deacetylase inhibitors (e.g., histone deacetylase inhibitors) and may be useful in the treatment of proliferative diseases such as cancer. In particular, the inventive compounds are HDAC6 inhibitors. The invention also provide synthetic methods for preparing the inventive compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.