Inventor · Weston, MA, US

James E. Bradner

34Patents
10h-index
35Co-inventors
71Inventor score

Filing activity: Mar 22, 2006 → Sep 28, 2020

Most-cited inventions

PatentTitleAreaCited byStatus
US8148526B1 Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof Chemistry; Metallurgy 32 Active
US8394810B2 Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof Chemistry; Metallurgy 30 Active
US8609678B2 Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof Chemistry; Metallurgy 27 Active
US8754237B2 Bifunctional histone deacetylase inhibitors Chemistry; Metallurgy 17 Active
US8999289B2 Treatment of protein degradation disorders Physics 15 Active
US8222423B2 Bifunctional histone deacetylase inhibitors Chemistry; Metallurgy 12 Active
US8383855B2 Histone deacetylase inhibitors Chemistry; Metallurgy 12 Active
US8440716B2 Deacetylase inhibitors and uses thereof Chemistry; Metallurgy 12 Active
US10849980B2 Methods to induce targeted protein degradation through bifunctional molecules Emerging Cross-Sectional Technologies 12 Active
US8304451B2 Histone deacetylase and tubulin deacetylase inhibitors Chemistry; Metallurgy 10 Active
US8716344B2 Class- and isoform-specific HDAC inhibitors and uses thereof Chemistry; Metallurgy 7 Active
US9572854B2 Treatment of protein degradation disorders Physics 5 Active
US11583586B2 Methods to induce targeted protein degradation through bifunctional molecules Emerging Cross-Sectional Technologies 3 Active
US10172905B1 Treatment of protein degradation disorders Physics 3 Active
US11059801B2 Methods to induce targeted protein degradation through bifunctional molecules Chemistry; Metallurgy 2 Active
US9199923B2 Histone deacetylase inhibitors Chemistry; Metallurgy 2 Active
US11285218B2 Degradation of bromodomain-containing protein 9 (BRD9) by conjugation of BRD9 inhibitors with E3 ligase ligand and methods of use Chemistry; Metallurgy 2 Active
US9434686B2 Deacetylase inhibitors and uses thereof Chemistry; Metallurgy 2 Active
US9540317B2 Class- and isoform-specific HDAC inhibitors and uses thereof Chemistry; Metallurgy 2 Active
US11311609B2 Regulating chimeric antigen receptors Chemistry; Metallurgy 1 Active
US9724321B2 Histone deacetylase inhibitors Chemistry; Metallurgy 1 Active
US9567301B2 Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors Chemistry; Metallurgy 0 Active
US11293023B2 Tunable endogenous protein degradation Chemistry; Metallurgy 0 Active
US12023385B2 Tunable endogenous protein degradation with heterobifunctional compounds Chemistry; Metallurgy 0 Active
US10059657B2 Class-and isoform-specific HDAC inhibitors and uses thereof Chemistry; Metallurgy 0 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.