Patent · US Active

Compounds for the treatment of inflammatory diseases

US8450355B2 · kind B2 · utility

0Cited by

14References

19Claims

0Family size

Assignee

Merck Sharp & Dohme LLC · US

Inventors

Michael K. C. Wong · New Brunswick, US
Wensheng Yu · Edison, US
Ling Tong · Hackettstown, US
Brian J. Lavey · New Providence, US
Bandarpalle B. Shankar · Readington, US
Joseph A. Kozlowski · Princeton, US
Seong Heon Kim · Livingston, US
Guowei Zhou · Somerville, US
De-Yi Yang · Morristown, US
Razia Rizvi · Bloomfield, US
Lei Chen · Singapore, SG
Aneta Maria Kosinzki · South Amboy, US
Kristin E. Rosner · Watertown, US
Luke Fire · Cambridge, US
Judson E. Richard · Kittery, US
Dansu Li · New York, US

Key dates

Filing date	Sep 22, 2009
Grant date	May 28, 2013
Priority date	—
Expiry date	Sep 22, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/048
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α combinations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.