2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
US8455451B2 · kind B2 · utility
88Cited by
6References
20Claims
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Key dates
| Filing date | Mar 17, 2011 |
| Grant date | Jun 4, 2013 |
| Priority date | — |
| Expiry date | Mar 17, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are select imidazo[1,2-f][1,2,4]triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 2′ position of the nucleoside sugar is substituted with halogen and carbon substituents. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections caused by both wild type and mutant strains of HCV.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.