Therapeutic compounds
US8455477B2 · kind B2 · utility
25Cited by
5References
7Claims
0Family size
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Key dates
| Filing date | Jul 27, 2009 |
| Grant date | Jun 4, 2013 |
| Priority date | — |
| Expiry date | Jul 27, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to pyrazolopyridines and imidazopyridines which are inhibitors of the kinase PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer. The compounds are also useful as inhibitors of other kinases such as FGFR3, NTRK3, RP-S6K and WEE1. Furthermore, the present compounds also selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.