Crystal structures of neuropilin fragments and neuropilin-antibody complexes
US8466264B2 · kind B2 · utility
8Cited by
14References
9Claims
0Family size
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Key dates
| Filing date | Jul 3, 2012 |
| Grant date | Jun 18, 2013 |
| Priority date | — |
| Expiry date | Jul 3, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides crystal structures of neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) fragments alone and in complex with anti-neuropilin antibodies, and method for their use. The invention further provides anti-Nrp antibodies and methods for their therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.